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Cancer centres join UK network

08/12/2003

Two Scottish Centres have been accepted as members of the UK wide National Translational Cancer Research Network (NTRAC) with the aim of improving cancer patients' access to new treatments by bridging the gap between scientific and clinical research.

One Centre will be based in Edinburgh, with a joint centre in Glasgow and Dundee, and will receive a total of £2.3 million of funding over 5 years from the Executive's Chief Scientist Office.

NHS clinical research staff will work together with scientists engaged in basic cancer research to help to ensure that advances in basic science reach patients faster.

Proposals for the Scottish centres include:

  • In Edinburgh, developing a database of information on patients with breast and colorectal cancer, in order to increase recruitment to early clinical trials. The data will be used to gain a better understanding of the causes of cancer and how it can be prevented or detected at an early stage
  • The Glasgow/Dundee Centre will look at the effect of new drug treatments alongside data on the properties of various types of tumour, in order to find out how different people respond to treatment

Health Minister Malcolm Chisholm said:

"Scotland has a reputation for excellence in both scientific and clinical cancer research. Our participation in this network will make it easier for the NHS to tap into the valuable work that is already being carried out in universities across Scotland and ensure that more patients benefit from the latest scientific advances.

"It will also help to ensure that clinical trials make use of the very latest advances from the laboratory and improve the quality of research being carried out.

"I look forward to seeing these Centres work together to ensure that Scotland remains at the forefront of developing innovative research into the prevention, detection and treatment of cancer."

NTRAC currently consists of 10 network centres in England and centres in Belfast and Cardiff, drawn from centres of excellence in cancer research.

It is part of the National Cancer Research Institute. A coordinating centre has been established at the University of Oxford which will provide the secretariat, communications hub and professional support for the network.

Each of the NTRAC centres has its own range of projects, however there are several key technologies and cross cutting programmes which provide the basis for collaboration.

Some of the current work of NTRAC includes:

  • Pharmacogenomics: The study of how an individual's whole genetic makeup affects their response to drugs
  • Tests that will allow clinicians to better determine who is at risk of cancer due to having a particular form of a gene, diagnose what subtype of cancer a patient has and select anti-cancer therapies on an individual basis
  • Development of new drug treatments

The Edinburgh Centre is a collaboration between Lothian University Hospitals NHS Trust, the University of Edinburgh, the MRC Human Genetics Trust and the Scottish Cancer Registry.

Over 170 individuals are actively involved in cancer research at the collaborating institutions. More information about the Edinburgh Centre can be obtained from Professor Malcolm Dunlop on 0131-467 8454 or 07904-100138

The Glasgow/Dundee Centre will consist of the Cancer Research UK Beatson Laboratories, the University of Dundee Medical School and the Beatson Oncology Centre and Department of Pathology based at the Western Infirmary in Glasgow.

The partners in the Centre host over 430 individuals actively involved in research from PHD students to nurses to consultants.

The National Cancer Research Institute (NCRI) is a partnership between Government, the voluntary sector and the private sector. It was established on April 1, 2001. Its aim is to streamline and accelerate the improvement of cancer research in the UK by taking a strategic oversight, identifying gaps in current research and opportunities for development.

The National Cancer Research Network was established in March 2002 and will receive £1m from the Executive. It aims to increase the recruitment of patients to large scale cancer trials.

Page updated: Wednesday, July 21, 2004