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Regulation 13(7)
SCHEDULE 3
Criteria for confirming the disease
1. Disease virus has been isolated from
an animal, any product derived from that animal, or its
environment.
2. Clinical signs consistent with the
disease are observed in a susceptible animal, and the viral
antigen or viral ribonucleic acid (
RNA) specific to one or more of the
serotypes of the disease virus has been detected and
identified in samples collected from the animal or animals
of the same epidemiological group.
3. Clinical signs consistent with the
disease are observed in a susceptible animal and the animal
or its cohorts have tested positive for antibody to the
disease virus structural or non-structural proteins,
provided that previous vaccination, residual maternal
antibodies or non-specific reactions can be excluded as
possible causes of seropositivity.
4. Viral antigen or viral
RNA specific to one or more of the
serotypes of the disease virus has been detected and
identified in samples collected from susceptible animals
and the animals are positive for antibody to disease virus
structural or non-structural proteins, provided that in the
case of antibodies to structural proteins previous
vaccination, residual maternal antibodies or non-specific
reactions can be excluded as possible causes of
seropositivity.
5. An epidemiological link has been
established to infected premises and at least one of the
following conditions applies-
(a) one or more animals are positive for antibody to
the disease virus structural or non-structural proteins,
provided that previous vaccination, residual maternal
antibodies or non-specific reactions can be excluded as
possible causes of seropositivity;
(b) viral antigen or viral
RNA specific to one of the serotypes of
the disease virus has been detected and identified in
samples collected from one or more susceptible animals;
(c) serological evidence of active infection with
the disease by detection of seroconversion from negative to
positive for antibody to the disease virus structural or
non-structural proteins has been established in one or more
susceptible animals, and previous vaccination, residual
maternal antibodies or non-specific reactions can be
excluded as possible causes or seropositivity (where a
previously seronegative status cannot be reasonably
expected, this detection of seroconversion is to be carried
out in paired samples collected from the same animals on
two or more occasions at least 5 days apart, in the case of
structural proteins, and at least 21 days apart, in the
case of non-structural proteins); or
(d) clinical signs consistent with the disease are
observed in a susceptible animal.
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